Clinical Study
Category
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27 March 2026
Forms of Presentation and Progression of Diabetes in Children Under One Year Old
A case series describing four infants under one year of age presenting with different forms of diabetes, including transient neonatal diabetes, IPEX syndrome, type 1 diabetes mellitus, and monogenic diabetes due to KCNJ11 mutation. The report highlights varied clinical presentations, diagnostic challenges, and the critical role of molecular testing in guiding accurate diagnosis, personalized treatment, and long-term management.
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18 March 2026
Atypical Presentation of Kawasaki Disease in a 4-Year-Old Child
A case report describing an atypical presentation of Kawasaki disease in a four-year-old child presenting with prolonged fever, conjunctival redness, rash, and mucocutaneous changes. The case highlights diagnostic challenges in incomplete Kawasaki disease and emphasizes early recognition and treatment with intravenous immunoglobulin to prevent coronary artery complications.
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18 March 2026
Adrenocortical Carcinoma Closely Mimicking a Pheochromocytoma: A Clinicopathologic Conundrum
A rare case of adrenocortical carcinoma (ACC) presenting clinically, biochemically, and radiographically as pheochromocytoma in a 49-year-old female with resistant hypertension and elevated urine metanephrines. The report highlights the diagnostic dilemma, multidisciplinary workup, and the importance of histopathology and immunohistochemistry in distinguishing adrenal cortical from medullary tumors.
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17 February 2026
Peripheral Facial Nerve Palsy as the Presenting Sign of Neurosyphilis: A Clinical Case
A clinical case of a 63-year-old female presenting with acute left-sided peripheral facial nerve palsy and incomplete eyelid closure. Diagnostic workup revealed axonal damage to the left facial nerve and serological confirmation of Treponema pallidum infection.
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11 February 2026
Prompt Identification and Management of Severe Hypoglycemia in a Phase III Diabetes Trial
This case study describes timely recognition, management, and reporting of severe hypoglycemia in a Phase III diabetes BA/BE trial, highlighting the role of clinical judgment, pharmacovigilance, and protocol adaptation to enhance participant safety.
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16 December 2025
Multidisciplinary Limb Salvage Protocols for Diabetic Foot Ulcers in Multi-Location Practices
This article presents a scalable, podiatry-led limb salvage protocol for diabetic foot ulcers across multi-location practices, highlighting outcomes from biologics, sharp debridement, irremovable offloading, glycemic optimization, and AI-supported telehealth, achieving over 90% limb salvage and reducing reulceration by 25–30% in real-world cases.

4 December 2025
Nasopharyngeal Pleomorphic Adenoma Progressing to Carcinoma ex Pleomorphic Adenoma with Metastases: A Case Report
This case report describes the first documented instance of a nasopharyngeal pleomorphic adenoma progressing to carcinoma ex pleomorphic adenoma (CXPA) with both regional and distant metastases.
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